Associations of low-level urine cadmium with kidney function in lead workers
نویسندگان
چکیده
منابع مشابه
Associations of low-level urine cadmium with kidney function in lead workers.
OBJECTIVES Low-level cadmium exposure, resulting in, for example, urinary cadmium <2.0 μg/g creatinine, is widespread; recent data suggest nephrotoxicity even at these low levels. Few studies have examined the impact of low-level cadmium exposure in workers who are occupationally exposed to other nephrotoxicants such as lead. METHODS We evaluated associations of urine cadmium, a measure of cu...
متن کاملLow-level cadmium exposure and effects on kidney function
OBJECTIVES The nephrotoxicity of cadmium at low levels of exposure, measured by urinary cadmium, has recently been questioned since co-excretion of cadmium and proteins may have causes other than cadmium toxicity. The aim of this study was to explore the relation between kidney function and low or moderate cadmium levels, measured directly in kidney biopsies. METHODS We analysed cadmium in ki...
متن کاملAssociations of patella lead and other lead biomarkers with renal function in lead workers.
OBJECTIVE We sought to compare associations of patella lead, which may represent a unique cumulative and bioavailable lead pool, with other lead measures in models of renal function. METHODS Renal function measures included blood urea nitrogen, serum creatinine, measured and calculated creatinine clearances, and urinary N-acetyl-beta-D-glucosaminidase (NAG) and retinol-binding protein. RESU...
متن کاملAssociations of lead biomarkers with renal function in Korean lead workers.
AIMS To compare associations of lead biomarkers with renal function in current and former lead workers. METHODS Cross sectional analysis of first year results from a longitudinal study of 803 lead workers and 135 controls in South Korea. Clinical renal function was assessed by blood urea nitrogen (BUN), serum creatinine, and measured and calculated creatinine clearance. Urinary N-acetyl-beta-...
متن کاملAssociations among Lead Dose Biomarkers, Uric Acid, and Renal Function in Korean Lead Workers
Recent research suggests that both uric acid and lead may be nephrotoxic at lower levels than previously recognized. We analyzed data from 803 current and former lead workers to determine whether lead biomarkers were associated with uric acid and whether previously reported associations between lead dose and renal outcomes were altered after adjustment for uric acid. Outcomes included uric acid...
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 2010
ISSN: 1351-0711
DOI: 10.1136/oem.2010.056077